Return to PND Info Home
PNDDB - MAO-A deficiency
OMIM 309850
Enzyme: Monoamine oxidase A (EC 1.4.3.4)
Reaction: Amine > (FAD) > Aldehyde
DD:
Diagnosis: Urine, DNA Urine: VMA (low), HVA (low), 5HIAA (low), Normetanephrine (high), 3-Methoxytyramine (high), Serotonin (high), Tyramine (high) DNA: see PNDDB
Clinical signs & symptoms: Aggresive behavior Mental retardation Limb hypertonia
Treatment:
Alternative treatment: Cyproheptadine Sertraline